Journal of Thyroid Disorders & Therapy offers the most comprehensive and reliable information pertaining to the latest developments in the field. The Journal also believes in advancing new hypotheses and opinions by means of its high quality Reviews, Perspectives, and Commentaries. Thus, the content published in the journal is original and comprehensive.

Thyroid eye disease (TED) is a complex orbital inflammatory disease causing inflammation in the extraocular muscles, eyelids, lacrimal glands, and surrounding connective and adipose tissue, which could be sight-threatening and disfiguring . TED is also known as Graves’ ophthalmopathy, named after Robert J. Graves . Most patients with TED have biochemical evidence of hyperthyroidism. TED may also occur in patients who have hypothyroidism or euthyroidism.

Uveitis is characterized by intraocular inflammation that might result from various systemic diseases. Patients of uveitis comorbidant with thyroid disease have been reported since 1915  and the association of thyroid disease with uveitis has recently received more attention . As the uvea is rich in blood vessels, immune system activation in one organ can result in hematogenous spread of inflammatory cells and cytokines into the eyes. Common pathophysiological mechanisms may be responsible for immune dysregulation in both thyroid disease and uveitis in certain individuals.

Although the serum auto antibodies that bind to ocular antigens discussed above are not disease-specific, a significant diversity of auto antibodies against a broad range of antigens has been detected in TED and uveitis patients. This nationwide cohort study also suggests that a history of TED is not significantly associated with uveitis. Different autoimmune mechanisms could explain the unique pathogenesis of both conditions. The present data warrant further exploration that different auto antibodies may be involved in the immunopathology of TED and uveitis.

Journal accepts original manuscripts in the form of research articles, review articles, Clinical reviews, commentaries, case reports, perspectives and short communications encompassing all aspects of related to Thyroid for publication in open access platform. All the manuscript published are available freely online immediately after publication without any subscription charges or registration.

Those who are interested to submit the editorials or their commentaries can submit at https://www.longdom.org/submissions/thyroid-disorders-therapy.htmlor you can mail through this mail id as an attachments  Thyroiddisorders@emedscholar.com

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Regards
Denise Williams
Editorial Manager     
Journal of Thyroid Disorders & Therapy
E-mail id: Thyroiddisorders@emedscholar.com